Peppers belong to the Solanaceae family and are highly valued worldwide for their flavor, nutritional content, and economic benefits. They contain various antioxidant compounds and vitamins associated with numerous health advantages, such as boosting metabolism and reducing inflammation. In addition, peppers are an important agricultural crop, contributing significantly to income along their value chain and serving as an indispensable ingredient in many dishes. However, domestic pepper production has steadily declined, mainly due to increased production costs. Peppers require a significant amount of labor during the harvest season, leading to high labor expenses. As a result, mechanized harvesting is emerging as a potential solution to address this issue. Research on mechanical harvesting of peppers has focused on developing harvesting machines, breeding suitable varieties, and exploring innovative cultivation methods appropriate for mechanization. Although similar research has been conducted in Korea, significant results have yet to be achieved. This review summarizes cases of mechanical pepper harvesting and outlines the traits and cultivation methods required for its effective implementation. For successful mechanical harvesting, the ideal cultivar should be suitable for once-over harvesting, with characteristics such as simultaneous and uniform ripening, low plant height, narrow branching angles, resistance to lodging, and ease of pedicel detachment from the stem. Moreover, fundamental research is essential for developing cultivation methods that do not rely on stacking and for determining optimal planting distances.